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Article

Mendelian Randomization Highlights the Causal Role of Normal Thyroid Function on Blood Lipid Profiles.

Endocrinology - 1 May 2021

Wang Yanjun, Guo Ping, Liu Lu, Zhang Yanan, Zeng Ping, Yuan Zhongshang

Abstract excerpt

The association between thyroid function and dyslipidemia has been well documented in observational studies. However, observational studies are prone to confounding, making it difficult to conduct causal inference. We performed a 2-sample bidirectional Mendelian randomization (MR) using summary statistics from large-scale genome-wide association studies of thyroid stimulating hormone (TSH), free T4 (FT4), and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33587120
DOI: 10.1210/endocr/bqab037

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