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Article

Assessing the Causal Effects of Adipokines on Uric Acid and Gout: A Two-Sample Mendelian Randomization Study.

Nutrients - 5 Mar 2022

Cong Ruyi, Zhang Xiaoyu, Song Zihong, Chen Shanshan, Liu Guanhua, Liu Yizhi, Pang Xiuyu, Dong Fang, Xing Weijia, Wang Youxin, Xu Xizhu

Abstract excerpt

Previous observational studies have highlighted associations between adipokines and hyperuricemia, as well as gout, but the causality and direction of these associations are not clear. Therefore, we attempted to assess whether there are causal effects of specific adipokines (such as adiponectin (ADP) and soluble leptin receptors (sOB-R)) on uric acid (UA) or gout in a two-sample Mendelian randomization (MR)...

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Identifiers

PMID: 35268067
DOI: 10.3390/nu14051091
PMCID: PMC8912555

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