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Causal relationship between serum uric acid and cardiovascular disease: A Mendelian randomization study

29 Jun 2024

Abstract excerpt

Observational studies have established an association between serum uric acid and cardiovascular disease (CVD). However, these studies are susceptible to uncontrolled confounders and reverse causality bias. To overcome these challenges, we employed a two-sample Mendelian randomization (MR) approach to investigate the causal link between serum uric acid and CVD. We utilized Genome-wide association study (GWAS)...

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PMID: 39411145
DOI: 10.1016/j.ijcha.2024.101453

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