Article
Causal relationships between rheumatism and dyslipidemia: A two-sample Mendelian randomization study.
Frontiers in endocrinology - 1 Jan 2022
Zhang Guangyang, Cai Yuanqing, Liang Jialin, Zhang Jianan, Jing Zhaopu, Lv Leifeng, Zhang Rupeng, Song Jidong, Dang Xiaoqian, Song Qichun
Abstract excerpt
Background: Dyslipidemia is often observed in rheumatic diseases, such as ankylosing spondylitis (AS), rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE), yet it remains to be detected whether rheumatic diseases have a causal effect on dyslipidemia. Methods: Significant (P < 5 × 10-8) and independent (r2 < 0.1) single-nucleotide polymorphisms in genome-wide association studies were selected as...
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