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Article

Associations between lipid-lowering drugs and urate and gout outcomes: a Mendelian randomization study.

Frontiers in endocrinology - 1 Jan 2024

Liu Min, Yin Na, Zhu Yuhang, Du Aili, Cai Chunyuan, Leng Pengyuan

Abstract excerpt

Objective: Gout is a common inflammatory arthritis and lipid metabolism plays a crucial role in urate and gout. Potential associations between urate and gout and lipid-lowering drugs have been revealed in observational studies. However, the effects of lipid-lowering drugs on urate and gout remain controversial. The aim of this study was to investigate the genetic association between lipid-lowering drugs and urate...

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Share to Gout
Share to Hydroxymethylglutaryl CoA Reductases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Membrane Transport Proteins

Share to Mendelian Randomization Analysis

Share to Proprotein Convertase 9

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Source

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Identifiers

PMID: 39926389
DOI: 10.3389/fendo.2024.1398023
PMCID: PMC11802419

Genes

HMGCR
PCSK9
NPC1L1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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