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Article

Causal Graph Among Serum Lipids and Glycemic Traits: A Mendelian Randomization Study.

Diabetes - 1 Aug 2022

Zhu Ziwei, Wang Kai, Hao Xingjie, Chen Liangkai, Liu Zhonghua, Wang Chaolong

Abstract excerpt

We systematically investigated the bidirectional causality among HDL cholesterol (HDL-C), LDL cholesterol (LDL-C), triglycerides (TGs), fasting insulin (FI), and glycated hemoglobin A1c (HbA1c) based on genome-wide association summary statistics of Europeans (n = 1,320,016 for lipids, 151,013 for FI, and 344,182 for HbA1c). We applied multivariable Mendelian randomization (MR) to account for the correlation among...

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Identifiers

PMID: 35622003
DOI: 10.2337/db21-0734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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