Article
Factor analysis in the Genetics of Asthma International Network family study identifies five major quantitative asthma phenotypes.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Mar 2008
Pillai S G, Tang Y, van den Oord E, Klotsman M, Barnes K, Carlsen K, Gerritsen J, Lenney W, Silverman M, Sly P, Sundy J, Tsanakas J, von Berg A, Whyte M, Ortega H G, Anderson W H, Helms P J
Abstract excerpt
BACKGROUND: Asthma is a clinically heterogeneous disease caused by a complex interaction between genetic susceptibility and diverse environmental factors. In common with other complex diseases the lack of a standardized scheme to evaluate the phenotypic variability poses challenges in identifying the contribution of genes and environments to disease expression. OBJECTIVE: To determine the minimum number of sets...
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