Article

Multiple broadly neutralizing antibody lineages can co-exist and mature in the same germinal centres

2025-11-10

Abstract excerpt

<h4>SUMMARY</h4> An efficacious HIV vaccine will need to generate broadly neutralizing antibodies (bnAbs) against distinct viral epitopes. To facilitate this, immunogens targeting precursor B cells of bnAbs have been developed. With this strategy, individual immunogens can even target multiple lineages, thereby beneficially limiting the number of immunogens needed for a multi-bnAb generating vaccine. However, it...

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Literature Corpus work: 1e92782a-5463-5881-8d6b-f05c8c041456
DOI: 10.1101/2025.11.09.687328

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