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Article

SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response.

Genes & development - 1 Aug 2003

An Jae Hyung, Blackwell T Keith

Abstract excerpt

During the earliest stages of Caenorhabditis elegans embryogenesis, the transcription factor SKN-1 initiates development of the digestive system and other mesendodermal tissues. Postembryonic SKN-1 functions have not been elucidated. SKN-1 binds to DNA through a unique mechanism, but is distantly related to basic leucine-zipper proteins that orchestrate the major oxidative stress response in vertebrates and...

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Identifiers

PMID: 12869585
DOI: 10.1101/gad.1107803
PMCID: PMC196237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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