Article

Accelerated Clonal Hematopoiesis in Pediatric and Young Adult Survivors of Childhood Cancer

2023-05-05

Abstract excerpt

Clonal hematopoiesis of indeterminate potential(CHIP) is a recognized consequence of aging and a precursor to myelodysplastic syndrome and acute myeloid leukemia which independently increases all-cause mortality in adults. Childhood cancer survivors experience a phenomenon of accelerated aging with increased all-cause mortality; however, the mechanism of this is not known and the prevalence of CHIP not well define...

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Literature Corpus work: 1de8110f-b26d-503e-bcc5-fc4b5ab0fadd
DOI: 10.1101/2023.05.03.23289475

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