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Article

Clonal hematopoiesis and associated diseases: A review of recent findings.

Cancer science - 1 Oct 2021

Asada Shuhei, Kitamura Toshio

Abstract excerpt

Recent genome-wide studies have revealed that aging or chronic inflammation can cause clonal expansion of cells in normal tissues. Clonal hematopoiesis has been the most intensively studied form of clonal expansion in the last decade. Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related phenomenon observed in elderly individuals with no history of hematological malignancy. The most frequently...

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Identifiers

PMID: 34328684
DOI: 10.1111/cas.15094
PMCID: PMC8486184

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