Article
Clonal Hematopoiesis: Updates and Implications at the Solid Tumor-Immune Interface.
JCO precision oncology - 1 Jun 2023
Buttigieg Marco M, Rauh Michael J
Abstract excerpt
Recent larger-scale studies of patients with cancer and longitudinal population cohorts have revealed how age-related expansions of mutant hematopoietic cells (clonal hematopoiesis [CH]) have differential associations with incident and prevalent cancers and their outcomes. Increasing recognition and deeper understanding of genetic subtypes of CH are yielding insights into the tumor-immune interface that may help...
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