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Implications of Clonal Hematopoiesis in Hematological and Non-Hematological Disorders

9 Dec 2024

Abstract excerpt

Clonal hematopoiesis (CH) is associated with an increased risk of developing myeloid neoplasms (MNs) such as myelodysplastic neoplasm (MDS) and acute myeloid leukemia (AML). In general, CH comprises clonal hematopoiesis of indeterminate potential (CHIP) and clonal cytopenia of undetermined significance (CCUS). It is an age-related phenomenon characterized by the presence of somatic mutations in hematopoietic stem...

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PMID: 39682303
DOI: 10.3390/cancers16234118

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