Article

Tracing relapse clone reveals complex recurrence patterns of pediatric acute lymphoblastic leukemia

2022-05-27

Abstract excerpt

<h4>Purpose: </h4> The recurrence is a significant impediment to the cure of pediatric acute lymphoblastic leukemia (ALL). We studied the correlation between the changes in the immunoglobulin ( Ig )/T-cell receptor ( TCR ) gene rearrangement patterns and clinical characteristics in the relapsed ALL in children. To determine where the relapsed clone originated, we traced the rearrangements levels dynamically from t...

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Literature Corpus work: 1dbb8b46-8e16-5404-b0a3-5e72ac70ee0c
DOI: 10.21203/rs.3.rs-1688524/v1

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