Article
TP53 alterations in relapsed childhood acute lymphoblastic leukemia.
Cancer science - 1 Jan 2020
Yu Chih-Hsiang, Chang Wan-Ting, Jou Shiann-Tarng, Lin Tze-Kang, Chang Ya-Hsuan, Lin Chien-Yu, Lin Kai-Hsin, Lu Meng-Yao, Chen Shu-Huey, Wu Kang-Hsi, Wang Shih-Chung, Chang Hsiu-Hao, Su Yi-Ning, Hung Chia-Cheng, Lin Dong-Tsamn, Chen Hsuan-Yu, Yang Yung-Li
Abstract excerpt
TP53 alterations are frequent relapse-acquired mutations in childhood acute lymphoblastic leukemia (ALL). The present study evaluated the clinical significance of relapsed childhood ALL in Taiwan. Diagnostic and/or relapsed bone marrow or peripheral blood was obtained from 111 children with relapsed ALL who were initially treated by using Taiwan Pediatric Oncology Group (TPOG) ALL protocols from January 1997 to...
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