Article

Identifying Differential Methylation in Cancer Epigenetics via a Bayesian Functional Regression Model

2021-03-22

Abstract excerpt

DNA methylation plays an essential role in regulating gene activity, modulating disease risk, and determining treatment response. Researchers can obtain insight into methylation patterns at a single nucleotide level utilizing next-generation sequencing technologies. However, complex features inherent in the data obtained via these technologies pose challenges beyond the typical big data problems. Identifying diffe...

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Literature Corpus work: 1d37b95f-523c-5650-828f-687a9098c686
DOI: 10.1101/2021.03.21.436232

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