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Article

A method to detect differentially methylated loci with next-generation sequencing.

Genetic epidemiology - 1 May 2013

Xu Hongyan, Podolsky Robert H, Ryu Duchwan, Wang Xiaoling, Su Shaoyong, Shi Huidong, George Varghese

Abstract excerpt

Epigenetic changes, especially DNA methylation at CpG loci have important implications in cancer and other complex diseases. With the development of next-generation sequencing (NGS), it is feasible to generate data to interrogate the difference in methylation status for genome-wide loci using cas...

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PMID: 23554163
DOI: 10.1002/gepi.21726
PMCID: PMC5896022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23554163-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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