Article
HMM-DM: identifying differentially methylated regions using a hidden Markov model
1 Jan 2016
Abstract excerpt
DNA methylation is an epigenetic modification involved in organism development and cellular differentiation. Identifying differential methylations can help to study genomic regions associated with diseases. Differential methylation studies on single-CG resolution have become possible with the bisulfite sequencing (BS) technology. However, there is still a lack of efficient statistical methods for identifying...