Back to search

Article

MethReg: estimating the regulatory potential of DNA methylation in gene transcription

2021-02-18

Abstract excerpt

Epigenome-wide association studies (EWAS) often detect a large number of differentially methylated sites or regions, many are located in distal regulatory regions. To further prioritize these significant sites, there is a critical need to better understand the functional impact of CpG methylation. Recent studies demonstrated CpG methylation-dependent transcriptional regulation is a widespread phenomenon. Here we p...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
c1007c46-37dd-5c1e-a0b4-aa7222cf2820
DOI
10.1101/2021.02.18.431696
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
MethReg: estimating the regulatory potential of DNA methylation in gene transcriptionDOI 10.1101/2021.02.18.431696
Select a neighboring publication to make it the new centre.