Article

Mapping the sequence logic of DNA repair enzyme binding reveals mechanistic principles and evolutionary links

2025-11-10

Abstract excerpt

<title>Abstract</title> <p>Mutations compromise genome stability, promote disease, and yet drive genetic diversity and evolution. DNA repair of mutagenic lesions acts to maintain genome integrity but is inherently imperfect, allowing mutations to emerge, persist and accumulate unevenly across the genome.Understanding when and where such mutations arise requires a deep understanding of the molecular factors that g...

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Literature Corpus work: 1d12dbaa-7fbb-5cfa-8149-d7f5bc5bd649
DOI: 10.21203/rs.3.rs-7972250/v1

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