Article

Modeling platinum resistance in a stem-like patient-derived ovarian cancer sample

2024-01-31

Abstract excerpt

<h4>Background</h4> Chemoresistance and tumor recurrence remain a significant challenge in ovarian cancer. Particularly in the context of platinum resistance, many mechanisms have been identified, including the activation of cellular processes like epithelial-mesenchymal transition (EMT), which generates cells with stemness characteristics. Current models of platinum resistance are limited or not adequate represe...

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Literature Corpus work: 1ccc7946-46b3-5946-84da-d7baf53b5c53
DOI: 10.1101/2024.01.30.577975

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