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Article

Isolation and characterization of stem-like cells from a human ovarian cancer cell line.

Molecular and cellular biochemistry - 1 Apr 2012

Wang Lijuan, Mezencev Roman, Bowen Nathan J, Matyunina Lilya V, McDonald John F

Abstract excerpt

Increasing evidence supports the existence of a subpopulation of cancer cells capable of self-renewal and differentiation into diverse cell lineages. These cancer stem-like or cancer-initiating cells (CICs) also demonstrate resistance to chemo- and radiotherapy and may function as a primary source of cancer recurrence. We report here on the isolation and in vitro propagation of multicellular ovarian cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22160925
DOI: 10.1007/s11010-011-1178-6

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CIC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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