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Three-Dimensional Tumor Models to Study Cancer Stemness-Mediated Drug Resistance

21 Feb 2024

Abstract excerpt

Solid tumors often contain genetically different populations of cancer cells, stromal cells, various structural and soluble proteins, and other soluble signaling molecules. The American Cancer society estimated 1,958,310 new cancer cases and 609,820 cancer deaths in the United States in 2023. A major barrier against successful treatment of cancer patients is drug resistance. Gain of stem cell-like states by...

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PMID: 38737455
DOI: 10.1007/s12195-024-00798-y

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