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Drug resistance and Cancer stem cells

15 Feb 2021

Abstract excerpt

Therapy resistance is a major problem when treating cancer patients as cancer cells develop mechanisms that counteract the effect of therapeutic compounds, leading to fit and more aggressive clones that contribute to poor prognosis. Therapy resistance can be both intrinsic and/or acquired. These are multifactorial events, and some are related to factors including adaptations in cancer stem cells (CSCs),...

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PMID: 33588867
DOI: 10.1186/s12964-020-00627-5

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