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Comprehensive review of drug resistance in mammalian cancer stem cells: implications for cancer therapy

18 Dec 2024

Abstract excerpt

Cancer remains a significant global challenge, and despite the numerous strategies developed to advance cancer therapy, an effective cure for metastatic cancer remains elusive. A major hurdle in treatment success is the ability of cancer cells, particularly cancer stem cells (CSCs), to resist therapy. These CSCs possess unique abilities, including self-renewal, differentiation, and repair, which drive tumor...

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PMID: 39695669
DOI: 10.1186/s12935-024-03558-0

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