Article

Cell-intrinsic platinum response and associated genetic and gene expression signatures in ovarian cancer cell lines and isogenic models

2024-07-29

Abstract excerpt

Ovarian cancers are still largely treated with platinum-based chemotherapy as the standard of care, yet few biomarkers of clinical response have had an impact on clinical decision making as of yet. Two particular challenges faced in mechanistically deciphering platinum responsiveness in ovarian cancer have been the suitability of cell line models for ovarian cancer subtypes and the availability of information on c...

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Literature Corpus work: 1702d001-7010-5e13-a8ae-ca8e150de523
DOI: 10.1101/2024.07.26.605381

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