Article

Modulators of the human voltage-gated proton channel Hv1

2025-06-18

Abstract excerpt

not-yet-known not-yet-known not-yet-known unknown The voltage-gated proton channel (Hv1) selectively transports protons (H⁺) across biological membranes in response to membrane potential changes. Hv1 assembles as a dimer and unlike most voltage-gated ion channels, it lacks a traditional central pore domain; instead, the voltage-sensing domain (VSD) of each monomer facilitates proton conduction via a hydrogen b...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1c8d02ad-04a9-502e-925f-ee9be4775bf6
DOI: 10.22541/au.175023587.77488082/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Modulators of the human voltage-gated proton channel Hv1DOI 10.22541/au.175023587.77488082/v1Read

Insights into the structure and function of HV1 from a meta-analysis of mutation studies.Semantic proximity Read

Biophysical Properties of Somatic Cancer Mutations in the S4 Transmembrane Segment of the Human Voltage-Gated Proton Channel hHV1.Semantic proximity Read

Targeting the Voltage-Dependent K+ Channels Kv1.3 and Kv1.5 as Tumor Biomarkers for Cancer Detection and PreventionSemantic proximity Read

Gating Currents in the Hv1 Proton Channel.Semantic proximity Read

Structural dynamics determine voltage and pH gating in human voltage-gated proton channelSemantic proximity Read

A voltage-gated proton-selective channel lacking the pore domain.Semantic proximity Read

Quantitative insights into the mechanism of proton conduction and selectivity for the human voltage-gated proton channel Hv1.Semantic proximity Read

Selectivity Mechanism of the Voltage-gated Proton Channel, HV1.Semantic proximity Read

The Roles of Proton-Sensing G-Protein-Coupled Receptors in Inflammation and CancerSemantic proximity Read

An aqueous H+ permeation pathway in the voltage-gated proton channel Hv1.Semantic proximity Read

A minireview on NHE1 inhibitors. A rediscovered hope in oncohematology.Semantic proximity Read

Diverse residues of intracellular loop 5 of the Na+/H+ exchanger modulate proton sensing, expression, activity and targeting.Semantic proximity Read