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Article

Gating Currents in the Hv1 Proton Channel.

Biophysical journal - 19 Jun 2018

De La Rosa Victor, Ramsey Ian Scott

Abstract excerpt

The Hv1 proton channel shares striking structural homology with fourth transmembrane helical segment-type voltage-sensor (VS) domains but manifests distinctive functional properties, including a proton-selective "aqueous" conductance and allosteric control of voltage-dependent gating by changes in the transmembrane pH gradient. The mechanisms responsible for Hv1's functional properties remain poorly understood,...

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Identifiers

PMID: 29925021
DOI: 10.1016/j.bpj.2018.04.049
PMCID: PMC6026397

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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