Article

Multiplexed Pan Soluble Ligandome Assaying via OASIS

2025-12-23

Abstract excerpt

<h4>ABSTRACT</h4> Screening soluble protein ligands is essential for understanding signaling interactions and enabling drug discovery. Currently, screens require arrayed formats because ligand diffusibility causes non-cell-autonomous effects. To enable multiplexed pooled assaying, we developed O bligate A utocrine S ignaling I n situ S creening (OASIS). Using lentiviral delivery of genetically barcoded ligan...

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Literature Corpus work: 1b2f48a0-4e54-5622-af72-3540b8cf3cea
DOI: 10.64898/2025.12.21.695830

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