Article
Construction and Screening of a Lentiviral Secretome Library.
Cell chemical biology - 22 Jun 2017
Liu Tao, Jia Panpan, Ma Huailei, Reed Sean A, Luo Xiaozhou, Larman H Benjamin, Schultz Peter G
Abstract excerpt
Over 2,000 human proteins are predicted to be secreted, but the biological function of the many of these proteins is still unknown. Moreover, a number of these proteins may act as new therapeutic agents or be targets for the development of therapeutic antibodies. To further explore the extracellular proteome, we have developed a secretome-enriched open reading frame (ORF) library that can be readily screened for...
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