Article

Spontaneous regression of micro-metastases following primary tumor excision: a critical role for primary tumor secretome

2020-03-13

Abstract excerpt

Numerous case studies have reported spontaneous regression of recognized metastases following primary tumor (PT) excision, but underlying mechanisms are elusive. Here we present a model of metastases regression and latency following PT excision, and identify potential underlying mechanisms. Using MDA-MB-231 HM human breast cancer cells that express highly sensitive luciferase, we were able to monitor early stages...

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Literature Corpus work: 1b2cefdf-2ecd-5abf-a7a9-2b397858cb9d
DOI: 10.1101/2020.03.12.986992

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