Article

Malignant epithelial diversification and inflammatory neutrophil remodeling define a transitional stage between tumor cell dissemination and overt metastatic outgrowth in breast cancer

2026-08-26

Abstract excerpt

Most disseminated cancer cells fail to progress to overt metastases, yet the biology that determines whether a disseminated cell remains dormant, dies, or advances toward metastatic outgrowth remains poorly defined, in part because this transitional window is difficult to capture experimentally. In breast cancer, where metastasis remains the primary driver of mortality, we leveraged a genetically engineered mouse...

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Literature Corpus work: a1e4846f-d594-5438-a890-4f0d5f7315fa
DOI: 10.64898/2026.08.25.747019

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