Article

Unveiling the role of osteosarcoma-derived secretome in premetastatic lung remodelling

2023-05-09

Abstract excerpt

Lung metastasis represents the leading cause of osteosarcoma-related death. Progress in preventing lung metastasis is pretty modest due to the inherent complexity of the metastatic process and the lack of suitable models. Herein, we provide mechanistic insights into how osteosarcoma systemically reprograms the lung microenvironment for metastatic outgrowth using metastatic mouse models and a multi-omics approach....

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Literature Corpus work: a68d74f9-8358-50a7-8ac9-e48468da4fe5
DOI: 10.1101/2023.05.06.539690

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