Article
Targeting metastatic cancer.
Nature medicine - 1 Jan 2021
Ganesh Karuna, Massagué Joan
Abstract excerpt
Despite recent therapeutic advances in cancer treatment, metastasis remains the principal cause of cancer death. Recent work has uncovered the unique biology of metastasis-initiating cells that results in tumor growth in distant organs, evasion of immune surveillance and co-option of metastatic microenvironments. Here we review recent progress that is enabling therapeutic advances in treating both micro- and...
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