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SMOC1 Regulates Endothelial-to-Mesenchymal Transition During Cardiac Repair After Myocardial Infarction

2025-12-12

Abstract excerpt

Endothelial-to-mesenchymal transition (EndMT) is a crucial, dual-phase process in cardiac repair after myocardial infarction (MI), driving both initial scar stabilization and subsequent pathological fibrosis. Therapeutic targeting requires precise temporal control rather than complete inhibition. This study identifies the matricellular protein SPARC-related modular calcium-binding protein 1 (SMOC1) as a novel regu...

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Literature Corpus work
1b004cf5-b362-5145-bca0-9d2546929a1b
DOI
10.64898/2025.12.10.693412
Open publication

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SMOC1 Regulates Endothelial-to-Mesenchymal Transition During Cardiac Repair After Myocardial InfarctionDOI 10.64898/2025.12.10.693412
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