Article
EMC10 (Endoplasmic Reticulum Membrane Protein Complex Subunit 10) Is a Bone Marrow-Derived Angiogenic Growth Factor Promoting Tissue Repair After Myocardial Infarction.
Circulation - 7 Nov 2017
Reboll Marc R, Korf-Klingebiel Mortimer, Klede Stefanie, Polten Felix, Brinkmann Eva, Reimann Ines, Schönfeld Hans-Joachim, Bobadilla Maria, Faix Jan, Kensah George, Gruh Ina, Klintschar Michael, Gaestel Matthias, Niessen Hans W, Pich Andreas, Bauersachs Johann, Gogos Joseph A, Wang Yong, Wollert Kai C
Abstract excerpt
BACKGROUND: Clinical trials of bone marrow cell-based therapies after acute myocardial infarction (MI) have produced mostly neutral results. Treatment with specific bone marrow cell-derived secreted proteins may provide an alternative biological approach to improving tissue repair and heart function after MI. We recently performed a bioinformatic secretome analysis in bone marrow cells from patients with acute MI...
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