Article

Variable methylation of endogenous retroviruses : epigenetic inheritance, environmental modulation, and genetic modifiers

2020-01-01

Abstract excerpt

Half of the mammalian genome is made up of transposable elements (TEs), the vast majority of which are modified by DNA methylation and repressive histone marks. Intracisternal A-particles (IAPs) are evolutionarily young murine-specific endogenous retroviruses (ERVs). Some are capable of retrotransposition and many harbour regulatory sequences with the potential to influence host gene expression. Previous work has...

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Literature Corpus work: 1aa6bb55-936e-553d-989f-08559e50f706
DOI: 10.17863/cam.50189

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