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Article

Epigenetic inheritance at the agouti locus in the mouse.

Nature genetics - 1 Nov 1999

Morgan H D, Sutherland H G, Martin D I, Whitelaw E

Abstract excerpt

Epigenetic modifications have effects on phenotype, but they are generally considered to be cleared on passage through the germ line in mammals, so that only genetic traits are inherited. Here we describe the inheritance of an epigenetic modification at the agouti locus in mice. In viable yellow ( A(vy)/a) mice, transcription originating in an intra-cisternal A particle (IAP) retrotransposon inserted upstream of...

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PMID: 10545949
DOI: 10.1038/15490

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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