Article
Is there a role for endogenous retroviruses to mediate long-term adaptive phenotypic response upon environmental inputs?
Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 5 Jan 2013
Sharif Jafar, Shinkai Yoichi, Koseki Haruhiko
Abstract excerpt
Endogenous retroviruses (ERVs) are long terminal repeat-containing virus-like elements that have colonized approximately 10 per cent of the present day mammalian genomes. The intracisternal A particles (IAPs) are a class of ERVs that is currently highly active in the rodents. IAP elements can influence the transcription profile of nearby genes by providing functional promoter elements and modulating local...
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