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Article

Retrotransposons as a major source of epigenetic variations in the mammalian genome.

Epigenetics - 1 Apr 2012

Ekram Muhammad B, Kang Keunsoo, Kim Hana, Kim Joomyeong

Abstract excerpt

Transcription of retrotransposons is usually repressed by DNA methylation, but a few elements, such as intracisternal A-particles (IAPs) associated with the Agouti and Axin-fused loci, partially escape this repression mechanism. The levels of this repression are also variable among individuals with an identical genome sequence, generating epigenetically different states of loci or 'epialleles.' In the current...

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PMID: 22415164
DOI: 10.4161/epi.19462
PMCID: PMC3368820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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