Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intracisternal A particle genes: Distribution in the mouse genome, active subtypes, and potential roles as species-specific mediators of susceptibility to cancer.

Molecular carcinogenesis - 1 Jan 2010

Qin Chunhua, Wang Zhibin, Shang Jin, Bekkari Kavitha, Liu Rong, Pacchione Stephen, McNulty Kathleen A, Ng Alan, Barnum John E, Storer Richard D

Abstract excerpt

Rodents, mice and rats in particular, are the species of choice for evaluating chemical carcinogenesis. However, different species and strains often respond very differently, undermining the logic of extrapolation of animal results to humans and complicating risk assessment. Intracisternal A particles (IAPs), endogenous retroviral sequences, are an important class of transposable elements that induce genomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chlorocebus aethiops
Share to COS Cells

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to Mice, Inbred BALB C

Share to Mice, Inbred C3H

Share to Mice, Inbred Strains

Share to Mutagenesis, Insertional

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 20025072
DOI: 10.1002/mc.20576

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intracisternal A particle genes: Distribution in the mouse genome, active subtypes, and potential roles as species-specific mediators of susceptibility to cancer.PMID 20025072Read ↗

Retrotransposons influence the mouse transcriptome: implication for the divergence of genetic traits.Semantic proximity Read ↗

Retroviral elements and their hosts: insertional mutagenesis in the mouse germ line.Semantic proximity Read ↗

Identification of autonomous IAP LTR retrotransposons mobile in mammalian cells.Semantic proximity Read ↗

Retrotransposons as a major source of epigenetic variations in the mammalian genome.Semantic proximity Read ↗

Variable methylation of endogenous retroviruses : epigenetic inheritance, environmental modulation, and genetic modifiersSemantic proximity Read ↗

A DNA transposon-based approach to validate oncogenic mutations in the mouse.Semantic proximity Read ↗

The mouse intracisternal A particle-promoted placental gene retrotransposition is mouse-strain-specific.Semantic proximity Read ↗

Transposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse modelSemantic proximity Read ↗

Genetic polymorphisms lead to major, locus-specific, variation in piRNA production in mouseSemantic proximity Read ↗

IAP display: a simple method to identify mouse strain specific IAP insertions.Semantic proximity Read ↗

Genome-wide assessments reveal extremely high levels of polymorphism of two active families of mouse endogenous retroviral elements.Semantic proximity Read ↗

A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.