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Variable DNA methylation of transposable elements: the case study of mouse Early Transposons.

Epigenetics - 1 Jan 2010

Reiss Daphne, Zhang Ying, Rouhi Arefeh, Reuter Max, Mager Dixie L

Abstract excerpt

Phenotypic variation stems from both genetic and epigenetic differences between individuals. In order to elucidate how phenotypes are determined, it is necessary to understand the forces that generate variation in genome sequence as well as its epigenetic state. In both contexts, transposable elements (TEs) may play an important role. It is well established that TE activity is a major generator of genetic...

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PMID: 20083901
DOI: 10.4161/epi.5.1.10631

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