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Diagnostic Accuracy of 1H-MRS in Detecting the Oncometabolite 2-Hydroxyglutarate (2HG) in Adult-Type Diffuse Gliomas

2026-04-01

Abstract excerpt

<title>Abstract</title> <p>Purpose To evaluate the diagnostic accuracy of three proton magnetic resonance spectroscopy (1H-MRS) strategies—short echo (TE 30 ms), intermediate echo (TE 97 ms), and MEGA-PRESS—for detecting the oncometabolite 2-hydroxyglutarate (2HG) to non-invasively determine isocitrate dehydrogenase (IDH) mutation status in adult-type diffuse gliomas. Methods A cohort of 152 patients with adult...

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Literature Corpus work
1a9b10c1-fff1-504e-a7fc-ac9160c4cb76
DOI
10.21203/rs.3.rs-9266342/v1
Open publication

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Diagnostic Accuracy of 1H-MRS in Detecting the Oncometabolite 2-Hydroxyglutarate (2HG) in Adult-Type Diffuse GliomasDOI 10.21203/rs.3.rs-9266342/v1
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