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Article

Highly specific determination of IDH status using edited in vivo magnetic resonance spectroscopy.

Neuro-oncology - 18 Jun 2018

Branzoli Francesca, Di Stefano Anna Luisa, Capelle Laurent, Ottolenghi Chris, Valabrègue Romain, Deelchand Dinesh K, Bielle Franck, Villa Chiara, Baussart Bertrand, Lehéricy Stéphane, Sanson Marc, Marjanska Malgorzata

Abstract excerpt

Background: Mutations in the isocitrate dehydrogenase (IDH) enzyme affect 40% of gliomas and represent a major diagnostic and prognostic marker. The goals of this study were to evaluate the performance of noninvasive magnetic resonance spectroscopy (MRS) methods to determine the IDH status of patients with brain gliomas through detection of the oncometabolite 2-hydroxyglutarate (2HG) and to compare performance of...

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Identifiers

PMID: 29126125
DOI: 10.1093/neuonc/nox214
PMCID: PMC6007442

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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