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Non-invasive Assessment of IDH-mutant Gliomas Using Optimized Proton Magnetic Resonance Spectroscopy on a Routine Clinical 3-Tesla MRI

2023-08-21

Abstract excerpt

<h4>Purpose: </h4> Isocitrate dehydrogenase (IDH) mutation has become one of the most important prognostic biomarkers in glioma management, indicating better treatment response and prognosis. IDH mutations confer neomorphic activity leading to the conversion of alpha-ketoglutarate (α-KG) to 2-hydroxyglutarate (2HG). The purpose of this study was to investigate the clinical potential of proton MR spectroscopy (1H-M...

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Literature Corpus work
0eb283ec-e101-5f5a-8afd-c6231af9d784
DOI
10.20944/preprints202308.1466.v1
Open publication

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Non-invasive Assessment of IDH-mutant Gliomas Using Optimized Proton Magnetic Resonance Spectroscopy on a Routine Clinical 3-Tesla MRIDOI 10.20944/preprints202308.1466.v1
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