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Article

2-Hydroxyglutarate MR spectroscopy for prediction of isocitrate dehydrogenase mutant glioma: a systemic review and meta-analysis using individual patient data.

Neuro-oncology - 12 Nov 2018

Suh Chong Hyun, Kim Ho Sung, Jung Seung Chai, Choi Choong Gon, Kim Sang Joon

Abstract excerpt

Background: Noninvasive and accurate modality to predict isocitrate dehydrogenase (IDH) mutant glioma may have great potential in routine clinical practice. We aimed to investigate the diagnostic performance of 2-hydroxyglutarate (2HG) magnetic resonance spectroscopy (MRS) for prediction of IDH mutant glioma and provide an optimal cutoff value for 2HG. Methods: A systematic literature search of Ovid-MEDLINE and...

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Identifiers

PMID: 30020513
DOI: 10.1093/neuonc/noy113
PMCID: PMC6231199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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