Article

A population-scale Red Blood Cell proteome atlas of 13,000 donors uncovers genetically encoded aging clocks predicting hemolysis, transfusion efficacy, and donor activity a decade later

2026-03-08

Abstract excerpt

<h4>Summary</h4> As the most abundant human cell and the foundation of transfusion medicine, red blood cells (RBCs) offer a unique readout of systemic health, yet they have never been characterized at population scale. We generated a proteome atlas of 13,091 blood donors with multi-omics longitudinal phenotyping, characterizing the influence of demographics and genetic variation on the reproducibility of RBC prot...

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Literature Corpus work: 1a053eae-21e4-5a16-8aff-e3da19273d85
DOI: 10.64898/2026.03.07.710284

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A population-scale Red Blood Cell proteome atlas of 13,000 donors uncovers genetically encoded aging clocks predicting hemolysis, transfusion efficacy, and donor activity a decade laterDOI 10.64898/2026.03.07.710284Read

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