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Proteomic analysis of red blood cells and the potential for the clinic: what have we learned so far?

4 Feb 2017

Abstract excerpt

INTRODUCTION: Red blood cells (RBC) are the most abundant host cells in the human body. Mature erythrocytes are devoid of nuclei and organelles and have always been regarded as circulating 'bags of hemoglobin'. The advent of proteomics has challenged this assumption, revealing unanticipated complexity and novel roles for RBCs not just in gas transport, but also in systemic metabolic homeostasis in health and...

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PMID: 28162022
DOI: 10.1080/14789450.2017.1291347

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