Article

Natural and age-related variation in circulating human hematopoietic stem cells

2023-11-30

Abstract excerpt

Hematopoietic stem and progenitor cells (HSPCs) deliver life-long multi-lineage output. However, with aging, we exhibit certain characteristic blood count changes and accumulation of clonal disorders. Better understanding of inter-individual variation in HSPC behavior is needed to understand these age-related phenomena and the transition from health to chronic and acute hematological malignancies. Here we study 62...

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Literature Corpus work: a21f9f0f-9fab-5b2c-b276-9d1d174460fe
DOI: 10.1101/2023.11.30.569167

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