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Arginine metabolism is a biomarker of red blood cell and human aging

30 Oct 2024

Abstract excerpt

Increasing global life expectancy motivates investigations of molecular mechanisms of aging and age-related diseases. This study examines age-associated changes in red blood cells (RBCs), the most numerous host cell in humans. Four cohorts, including healthy individuals and patients with sickle cell disease, were analyzed to define age-dependent changes in RBC metabolism. Over 15,700 specimens from 13,757 humans...

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Share to Epigenetics and DNA Methylation
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PMID: 39478346
DOI: 10.1111/acel.14388

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